Adaptation, evolution and innovation
Our commitment to the ophthalmology community is independent of the product cycle or short term financial opportunity. We understand that adaptation and evolution of therapies are as crucial in ophthalmology as pure innovation.
As well as our range of pharmaceuticals, we have developed a number of technologies to improve the outcome and experience for the patient using our products.
Santen led the market to widespread development of preservative-free ophthalmology therapies, particularly for glaucoma and dry eye disease (DED). Santen introduced the first preservative-free prostaglandin for the treatment of glaucoma. Preservative-free products help reduce irritation and damage from long term use, encouraging better patient adherence. A wider range of patients can benefit from these products, because they have a lower potential for adverse events. Santen is introducing preservative-free, multidose formats of a number of products in the portfolio.
Santen Dropaid® delivery devices
Dropaid® delivery aids have exclusively been developed for use in combination with Santen products. Dropaid delivery aids are especially helpful for patients with weak or unsteady fingers or hands. It is a medical device used with both Santen's single-dose and multidose (preservative-free) containers.
Dropaid® single-dose is a delivery aid for eye drops in a single-dose container. It helps the patient to instil eye drops from a single-dose container.
Dropaid® single-dose is suitable with Cosopt®, Fotil®, Fotil® forte, Lecrolyn®, Loyada®, Oftan® Timolol, Oftaquix®, Optimol®, Saflutan®, Taflotan®, Taptiqom®, Timoptic®, Trusopt® products in single-dose containers.
DropAid for Santen’s single-dose eye drops
Dropaid® multidose is a delivery aid for eye drops in a preservative-free multidose container. It helps the patient to instill eye drops from a preservative-free multidose container.
Dropaid® multidose is suitable with Cationorm®, Cosduo®, Cosidime®, Cosopt®, Costec®, Hyprosan®, Lecrolyn®, Lecrosine® Safluround®, Saflutan®, Taflotan® products in preservative-free multidose containers.
DropAid for Santen preservative-free multidose eye drops
Santen's preservative-free multidose containers
We know that use of many medicines may be less frequent or in lower quantities than is recommended or prescribed, so Santen has taken a number of steps to reduce any cause of reduced patient adherence.
Ease of handling is an important influence on bottle design with patients wanting a bottle that is easy to open, hold and use. Our Dimple™ bottle was designed to overcome problems with opening the bottle and controlling the drops so they reach the eye and are dispensed in the right quantity.
The Dimple™ bottle has an easy grip shape and controlled dropping with an easy squeeze bottle that’s responsive to pressure. It’s also easier to open because of edges on the cap.
Novasorb is our unique patented technology that helps improve the time that eye drops remain in the eye, helping reduce loss of product through blinking. We developed this cationic oil-in-water emulsion jointly with Novagali (now integrated as a Santen company), for use in various eye drop products in the portfolio. Novasorb improves bioadsorption, spreading on the ocular surface and residence time (the length of time the medication remains on the ocular surface). It can reduce frequency of eye drop application for patients.
We are developing the CE-marked medical device MicroShunt as a surgical implant for lowering intraocular pressure by promoting better drainage of aqueous humour from the eye. Designed using an innovative and bio-inert material, the device is implanted using minimally invasive surgery. The MicroShunt device is expected to offer a new surgical option for treating glaucoma.
Preservative free bottles
Santen has worked with partners to develop multidose bottles for preservative free eye drops, ensuring microbiological safety along with ease of use for patients.
See more about Santen’s two preservative free, multi-dose bottles here:
Intraocular lens (IOL)
Santen is introducing xact™ Mono-EDoF™ a CE marked and approved monofocal, hydrophobic intraocular lens (IOL). The xact™ Mono-EDoF™ is a hydrophobic diffractive IOL with 4 diffractive rings developed by Santen in collaboration with Advanced Vision Science.1 For ophthalmologists, this new type of monofocal lens will mean the ability to offer their patients more than just standard vision correction following cataract surgery. For patients, the implanted xact™ Mono-EDoF™ should reduce their dependence on glasses after cataract surgery.2
1. Baur I, et al. Klinische erfahrung mit einer neuen monofokalen intraokularlinse mit erweiterter tiefenscharfe. Presented at the 32nd annual Internationaler Kongress der Deutschen Ophthalmochirugen, Nuremberg, Germany, 24 May 2019.
2. Spalton DJ, et al. Optical and Clinical Comparison of a Novel Monofocal Extended-Depth-of-Focus IOL and a Conventional Bifocal Extended-Depth-of-Focus IOL. Presented at American Society of Cataract & Refractive Surgery, San Diego, US, 4 May 2019.